Samantha Reid (January 4, 1984 – January 17, 1999) grew up in the Detroit, Michigan Metropolitan Area. She came to national attention after her death at the age of 15.
In the company of three young men at another man's apartment, Samantha and her friends, Melanie and Jessica, were offered drinks. Samantha and Melanie asked for Mountain Dew - Jessica asked for a Screwdriver (orange juice and vodka). The young men brought them the beverages, to which they had added either gamma-hydroxybutyric acid (GHB) or gamma-butyrolactone (GBL). Melanie stated that her face had become numb soon after, and then both of the girls passed out. The boys at first did not think anything was wrong, since both GHB and alcohol can cause those drinking them to pass out if they drink too much of it and this is not usually a medical emergency. However, Jessica noticed later that they were having difficulty breathing. The boys eventually drove her to the hospital, but Samantha stopped breathing on the way there. Both of the young women were put on life-support, but Samantha died roughly eighteen hours later.
The three young men who poisoned her were found guilty of poisoning and involuntary manslaughter, while the older man who owned the apartment was found guilty of an accessory charge, and possession of GHB. They were sentenced to 5–15 years in prison.
Reid's death inspired the legislation titled the Hillory J. Farias and Samantha Reid Date-Rape Drug Prohibition Act of 2000. This law categorized GHB as a Schedule I controlled substance according to the Controlled Substance Act.